Proactive management of toxicities can reduce treatment interruptions and potentially help preserve performance status during CRT1-3

Techniques to Proactively Manage Adverse Events in Unresectable Stage 3 NSCLC Patients on Concurrent CRT

... if we give appropriate management, you can treat through almost any Grade 3 toxicity.

–Dr Kristin Higgins*

Examples of proactive management strategies for esophagitis2

Dietary modifications

  • Soft foods
  • Bland foods
  • High-calorie foods
  • High-protein supplements
Examples of proactive

Pharmacologic interventions

  • Antacids
  • Proton pump inhibitors
  • Promotility agents
  • “Magic” or “miracle” mouthwash

Expert Discussion on Management Strategies for Specific Adverse Events

  • Constipation
  • Diarrhea
  • Nausea/vomiting
  • Radiation dermatitis

Importance of Proactive AE Management and Patient Education for Concurrent CRT in Unresectable Stage 3 NSCLC

…It’s a good time to remind them (patients) of what’s coming, to talk about prophylactic measures…to say, do you know who to call if you’re having a problem.

–Dr Roy Decker*

CRT=chemoradiotherapy; NSCLC=non-small cell lung cancer; AE=adverse event; NCCN=National Comprehensive Cancer Network.

*The views and opinions expressed in the Art of CRT video series are those of the individual panel members and do not represent the views or opinions of AstraZeneca. These videos contain anecdotal information gathered from a discussion with 8 physicians and nurses based on their opinions/experiences. Recommendations are general and may vary with patients.

References: 1. Verma V, Simone CB, Werner-Wasik M. Acute and late toxicities of concurrent chemoradiotherapy for locally-advanced non-small cell lung cancer. Cancers. 2017;120(9). 2. Poirier P. Nursing-led management of side effects of radiation: evidence-based recommendations for practice. Nursing: Research and Reviews. 2013;3:47-57. 3. Poirier P. Factors affecting performance of usual activities during radiation therapy. Oncol Nurs Forum. 2007;34(4):827-834.